摘要嗜酸性粒细胞性胃肠炎(EGE)是一种儿童相对少见的良性慢性胃肠道炎性疾病,以胃肠道嗜酸性粒细胞(EOS)浸润为特征,临床表现因浸润部位及层次不同而呈多样性,内镜下表现无特异性,EGE的确诊主要依据消化道症状、大量EOS组织学浸润,以及除外引起胃肠道组织EOS浸润的其他疾病.治疗包括膳食疗法、糖皮质激素、抗过敏药物、免疫调节疗法等.尽管膳食疗法和糖皮质激素治疗可改善大多数患儿的临床症状,但常需要长期地维持治疗和随访,以防止复发.出现并发症者,如狭窄、穿孔、梗阻等,则需要外科干预.

abstractsEosinophilic gastroenteritis is a relatively rare chronic gastrointestinal inflammatory disease in children,characterized by gastrointestinal eosinophil infiltration.Clinical manifestations due to infiltration of different sites and levels were diverse,endoscopic performance is often nonspecific,the diagnosis of eosinophilic gastroenteritis is mainly based on gastrointestinal symptoms,a large number of eosinophil histological infiltration,and exclude other diseases that cause eosinophil infiltration in gastrointestinal tissue.Treatments include diet therapy,glucocorticoids,anti-allergy drugs,immunomodulatory therapies.Although diet therapy and glucocorticoid treatment improve clinical symptoms in most children,long-term maintenance therapy and follow-up are often required to prevent recurrence.In children with serious complications,such as perforation and obstruction,may require surgery and other treatments.