摘要6群肺炎链球菌是导致儿童社区感染的常见血清群之一，既往采用荚膜肿胀实验将6群分为6A和6B 2个亚型。随着基因测序分型方法的应用，近年来又发现了6C、6D、6E、6F和6H等新的亚型。肺炎链球菌结合疫苗(PCV)7应用后的国家或地区监测到6C型呈增长的趋势，应引起重视。现就6群肺炎链球菌新亚型的荚膜多糖合成基因、荚膜多糖结构、耐药性及分子流行病学进行阐述。

abstractsSerogroup 6 Streptococcus pneumoniae is one of the common serogroups that lead to community acquired infections in children, and was divided into 6A and 6B serotypes by quellung reaction.With the application of typing methods by gene sequencing, new serotypes such as 6C, 6D, 6E, 6F and 6H have been discovered in recent years.The increase of 6C subtype in the countries or regions after the introduction of pneumococcal conjugated vaccine(PCV)7 should be emphasized.In this paper, the capsular polysaccharide synthesis genes, structure of capsular polysa-ccharide, antimicrobial resistance and molecular epidemiology of new serotypes of serogroup 6 Streptococcus pneumoniae were discussed.