摘要卡介苗(BCG)是目前唯一有效且广泛使用的抗结核病疫苗。近年来,研究者们一直致力于开发针对结核病的新型疫苗,但研究结果却不尽如人意;这使得人们开始重新审视并研究BCG这一应用了近百年的疫苗。现从BCG的起源和进化、引起的免疫反应、免疫保护力及其复种等几个方面,对BCG免疫预防研究最新进展进行阐述。
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abstractsBacillus Calmette-Guerin (BCG) is the only effective and widely used tuberculosis(TB) vaccine.In recent years, researchers have been working on developing novel TB vaccines, but the results are still far from satisfactory.This makes people start to re-examine the BCG vaccine, which has been used for nearly a hundred years.This review will summarize the origin and evolution, immune response, immune protection and revaccination of BCG, and describe the latest progress in immune prophylaxis of BCG.
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