摘要侵袭性真菌病(IFD)发病率呈持续上升趋势，尤其是在免疫功能低下的人群。由于症状不典型，明确病原诊断困难，随着抗真菌耐药性不断升高，IFD的诊断和治疗面临着极大挑战。2022年世界卫生组织制定了第1份真菌重点病原清单，列出最需要关注的真菌病原体并进行总结，进一步促进了解IFD的流行病学、抗真菌药物耐药情况，为制定IFD预防、控制干预措施提供依据。

abstractsThe global morbidity of invasive fungal diseases (IFD) tends to increase, especially in immunocompromised people.Due to the atypical symptoms, unclear etiological mechanism, and emerging antifungal resistance, IFD challenge current clinical diagnosis and treatment.The World Health Organization (WHO) developed the first WHO fungal priority pathogens list in 2022.The most concerning fungal pathogens were listed and summarized to promote further understanding of the epidemiology of IFD and antifungal drug resistance.It is hoped to provide a basis for the prevention and interventions of IFD.