摘要目的 探讨安尔碘Ⅲ型溶液外敷治疗急性痛风性单关节炎的效果.方法 将109例急性痛风性单关节炎患者按随机数字表法分为扶他林组56例和安尔碘组53例,安尔碘组用安尔碘Ⅲ型溶液湿纱布外敷红肿关节30 min,扶他林组使用扶他林乳膏外涂红肿关节,比较2组治疗前后的疼痛、红肿症状及7 d后局部治疗效果.结果 治疗24、72 h安尔碘组疼痛评分分别为(3.44 ± 0.89)、(2.43 ± 0.73)分,较治疗前的(6.14 ± 0.98)分好转(t=2.375、3.393,P＜0.01),扶他林组分别为(3.85 ± 0.74)、(3.14 ± 0.68)分,较治疗前的(6.07 ± 1.00)分好转(t=2.208、3.120,P＜0.01),安尔碘组治疗24、72 h疼痛效果优于扶他林组(t=4.781、8.380,P＜0.01).治疗24、72 h安尔碘组红肿评分分别为(1.57 ± 0.70)、(1.13 ± 0.35)分,较治疗前的(2.11 ± 0.62)分好转(t=0.589、0.964,P＜0.01),扶他林组分别为(1.95 ± 0.73)、(1.61 ± 0.49)分,治疗72 h红肿评分较治疗前的(2.05 ± 0.56)分好转(t=0.623,P＜0.01),安尔碘组治疗24、72 h消肿效果优于扶他林组(t=3.379、4.290,P＜0.01).安尔碘组7 d局部疗效治愈28例,显效15例,有效11例,无效2例,总有效率达96.4%(54/56),扶他林组治愈23例,显效11例,有效10例,无效9例,总有效率为83.0%(44/53),2组7 d局部疗效比较差异有统计学意义(χ2=4.019,P＜0.05).结论 安尔碘Ⅲ型溶液能减轻急性痛风性单关节炎的症状,对急性痛风性单关节炎的局部疗效优于扶他林乳膏外涂疗效.

abstractsObjective To investigate the effect of Anerdian type III solution on the treatment of acute gouty monoarthritis. Methods Total 108 cases of acute gouty monoarthritis were divided into two groups according to the method of random number table, including 56 cases in the Anerdian group and 53 cases in the Votalin group, respectively. The Anerdian group was applied Anerdian type III solution to compress the swelling joint wet for 30 minutes, while the Votalin group was given Votalin Emulgel for external application in the swollen joint. Then the scores of pain and redness were calculated, and the effects of local treatment were compared directly before and after the treatment, and these variables were also compared after 7 days. Results 24 hours and 72 hours after the treatment, the pain score in the Anerdian group was 3.44 ± 0.89 and 2.43 ± 0.73 (t=2.375, 3.393, P<0.01), while the pain score in the Votalin group was 3.85 ± 0.74 and 3.14 ± 0.68 (t=2.208, 3.120, P<0.01), respectively, which referred to improvement in both groups.And the score of redness in the Anerdian group was 1.57 ± 0.70 and 1.13 ± 0.35 (t=0.589, 0.964, P<0.01), while the score of redness in the Votalin group was 1.95 ± 0.73 and 1.61 ± 0.49 (t=0.151, 0.623, P=0.091, P<0.01) respectively. 24 hours and 72 hours after the treatment, the score of redness in the Anerdian group was smaller than that in the Votalin Group (t=3.379, 4.290, P<0.01). In Anerdian group, local treatment showed fully cured in 28 cases, marked effective in 15 cases, effective in 11 cases, not effective in 2 case, and total effective rate was 96.4% (54/56) after 7 days′treatment, while in Votalin group, local treatment revealed fully cured in 24 cases, marked effective in 11 cases, effective in 8 cases, not effective in 9 case, and total effective rate was 83.0% (44/53). There was statistically significant difference between the two groups in local treatment ( χ2=4.019, P<0.05). Conclusion Anerdian type III solution can alleviate the symptoms of acute gouty unilateral arthritis quickly. It hasbetter curative effect on local treatment of acute gouty monoarthritis than Votalin.