摘要目的:收集并总结国内外糖尿病患者胰岛素注射相关锐器废物处置管理的相关证据，为临床医护人员提供参考。方法:本研究为循证研究。系统检索国内外数据库和专业网站，纳入关于胰岛素注射相关锐器废物处置与管理相关文献，包括指南、专家共识、证据总结、最佳实践信息册、推荐实践、临床决策和系统评价，检索时限为建库至2021年12月。对符合标准的文献进行质量评价后提取和汇总证据。结果:共纳入15篇文献，总结出包括胰岛素注射相关锐器废物的风险评估与管理、教育培训、使用安全型器械与使用锐器回收容器4个方面的25条最佳证据。结论:胰岛素注射相关锐器废物处置管理的最佳证据为医护人员的临床实践提供证据支持，以规范糖尿病患者锐器废物的处置实践。

abstractsObjective:To retrieve and summarize the best evidence related to the management of insulin injection-related sharps waste disposal in diabetic patients at home and abroad, so as to provide reference for clinical healthcare professionals.Methods:This was a evidence-based research. Evidence on insulin injection-related sharps waste management in patients with diabetes, including guidelines, expert consensus, evidence summaries, best practice information sheet, recommended practices, clinical decisions and systematic reviews was systematically searched from domestic and international databases and professional websites, and the search time frame was from the establishment of the database to December 2021. Evidence was extracted and summarized following a quality evaluation of the literature that met the criteria.Results:A total of 15 papers were included, summarizing 25 pieces of best evidence on four areas including risk assessment and management of sharps waste associated with insulin injections, education and training, and the use of safe devices and sharps containers.Conclusions:Best evidence on the management of insulin injection-related sharps waste disposal provides evidence to support clinical practice for healthcare professionals to standardized sharps waste disposal practices in patients with diabetes.