摘要目的:分析健康促进生活方式、患者积极度对PICC置管肿瘤患者化疗间歇期导管自我管理能力的影响以及作用路径，为制订针对性干预措施提供依据。方法:选取2021年1月至2022年12月天津市第三中心医院收治的化疗间歇期PICC置管肿瘤患者作为调查对象，使用一般资料调查表、肿瘤患者PICC自我管理能力量表、健康促进生活方式量表Ⅱ、患者积极度量表对其进行横断面调查。采用Pearson相关性分析、多元线性回归分析分析数据，并构建影响因素之间的结构方程模型。结果:最终纳入251例PICC置管肿瘤患者，其导管自我管理能力得分为（153.12 ± 20.33）分，健康促进生活方式得分为（98.58 ± 16.05）分，患者积极度标准化得分为（50.52 ± 6.51）分。PICC置管肿瘤患者导管自我管理能力各维度得分及总分、患者积极度得分和健康促进生活方式得分之间两两呈正相关（ r值为0.503~0.910，均 P<0.01）。多元线性回归分析显示，健康促进生活方式、患者积极度是患者导管自我管理能力的影响因素（ t=2.67、13.65，均 P<0.05）。路径分析显示，患者积极度在健康促进生活方式和导管自我管理能力之间起部分中介作用，效应值为0.33（95% CI 0.301~0.557），占总效应的46.5%。 结论:健康促进生活方式、患者积极度是PICC置管肿瘤患者化疗间歇期导管自我管理能力的影响因素，患者积极度在健康促进生活方式与导管自我管理能力之间起部分中介作用。

abstractsObjective:To analysis the effect of health-promoting lifestyle and patient activation on self-management among tumor patients with PICC of the intermission of chemotherapy, so as to provide a basis for the targeted caring intervention programs.Methods:Using cross-sectional survey methods, from January 2021 to December 2022, the tumor patients with PICC of the intermission of chemotherapy of Tianjin Third Central Hosptial were investigated, using the General Demographic Questionnaire, Cancer Patients PICC Self-management Scale, Health Promotion Lifestyle Profile Ⅱ and Patient Activation Measure. Pearson correlation analysis and multiple linear stepwise regression analysis were used to analyze the data, and the structural equation model between related factors were established.Results:A total of 251 patients were collected in the this study, the scores of self-management were (153.12 ± 20.33) points, health-promoting lifestyle were (98.58 ± 16.05) points, and patient activation were (50.52 ± 6.51) points. The dimensions scores and total scores of self-management were positively correlated with the health-promoting lifestyle and patient activation in tumor patients with PICC ( r values were 0.503-0.910, all P<0.01). Multiple linear regression analysis showed that the health-promoting lifestyle and the patient activation were the influencing factors of the patient's self-management ability ( t=2.67, 1365, both P<0.05). Pathway analysis results showed that patient activation played a partially mediating role between health-promoting lifestyle and self-management, the effect value was 0.33 (95% CI 0.301-0.557), accounting for 46.5% of the total effect. Conclusions:Health-promoting lifestyle and the patient activation were the influencing factors of the self-management ability of tumor patients with PICC, patient activation played a partially mediating role between health-promoting lifestyle and self-management.