换一批摘要本文主要综述目前国内外带状疱疹后神经痛（PHN）动物模型制作的研究进展，重点介绍由水痘-带状疱疹病毒（VZV）与单纯疱疹病毒Ⅰ型（HSV1）诱发的PHN动物模型的建立方法和疼痛行为学表现。旨在比较现有PHN动物模型的研究概况，为进一步阐明PHN致病机制提供有效的研究工具，同时也为PHN动物模型的选择和改良提供参考。
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abstractsThis review mainly introduced the research progresses in the establishment of postherpetic neuralgia (PHN) animal model at home and abroad, with emphasis on the establishment methods and pain behaviors of PHN animal model induced by varicella zoster virus (VZV) or herpes simplex virus 1 (HSV1). The aims of this paper were to compare the current research status of PHN animal model, and to provide effective research tool for further elucidating the pathogenic mechanism of PHN, and reference for selecting and improving the PHN animal model.
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关键词
神经痛,带状疱疹后疾病模型,动物水痘-带状疱疹病毒单纯疱疹病毒Ⅰ型Neuralgia, postherpeticDisease models, animalVaricella zoster virusHerpes simplex virus type 1
栏目名称
DOI
10.3760/cma.j.cn101658-20200811-00141
发布时间
2023-04-25（万方平台首次上网日期，不代表论文的发表时间）
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