摘要Objective To evaluate levels of the circulating antisperm antibody (ASA ) in women with secondary infertility.Methods Eighty-three women defined as secondary infertility were enrolled into this study.Based on their outcomes of previous pregnancy,these women were divided into two groups:group HC (having at least one child,n=45),group NC (no child but one to three abortions,n=35).The serum was screened by the indirect immunobead test for ASA type IgG and IgA according to the WHO laboratory manual.Results Of the 83 patients assessed for ASA-IgG,14 had immunobead binding rate ranged from 15％ to 43％,and the sub-positive rate was 16.9％.Five cases showed ASA-IgA sub-positive,and had binding rate between 10％ and 20％.No case had the clinical positive level according to the WHO criteria.No differences were found on ASA-IgG and ASA-IgA between HC and NC groups (P＞0.05).Conclusion The circulating ASA may be a possible cause to decrease fertilityin women with secondary infertility.