换一批
换一批摘要肥胖和体脂代谢是困扰多囊卵巢综合征(PCOS)患者的主要问题之一,是引起PCOS远期并发症的重要因素.PCOS女性的肥胖比例普遍高于正常女性,且多表现为特征性的腹型肥胖.腹部脂肪量独立于全身脂肪量,与糖、脂代谢紊乱、胰岛素抵抗、高雄激素血症呈正相关.了解体脂分布在PCOS发病中的作用对其治疗具有重要意义.
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abstractsObesity and dysfunctional lipid metabolism are core problems of polycystic ovary syndrome (PCOS) patients and key risk factors for complications of PCOS.PCOS women have a higher incidence of obesity than healthy women and usually exhibit as abdominal obesity.Abdominal fat is independent from body fat,but correlates with impairment in glucose and lipid metabolism,insulin resistance and hyperandrogenemia.Understanding how body fat distributes to the pathogenesis of PCOS is crucial for developing therapeutic interventions.
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关键词
多囊卵巢综合征体脂分布胰岛素抵抗腹型肥胖Polycystic ovary syndromeBody fat distributionInsulin resistanceAbdominal obesity
栏目名称
综述
DOI
10.3760/cma.j.issn.2096-2916.2019.10.013
发布时间
2019-12-26
基金项目
北京市自然科学基金
国家自然科学基金(81603446)Beijing Municipal Natural Science Foundation
National Natural Science Foundation of China
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