胚胎植入前基因检测技术在体外受精-胚胎移植中的应用现状
Application of preimplantation genetic testing technique in in vitro fertilization and embryo transfer
摘要胚胎植入前基因检测技术发展至今已在辅助生殖领域广泛应用,研究者们也不断地在优化该技术以期得到更好的应用。从最初只能检测有限数目的染色体检查逐渐优化为全基因组筛查技术,胚胎检测方法也由侵入性向非侵入性的方法开始转变,生殖中心对胚胎植入前基因检测技术的临床应用结局均有报道。通过对比不同中心的研究结果,我们了解到不同诊断技术、检测技术还有新近出现的改良技术各自的优势和局限性。本文结合胚胎植入前基因检测技术发展的过程,对目前临床应用胚胎移植前遗传学检测技术的研究进展进行综述。
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abstractsPreimplantation genetic testing technology has been widely used in the field of assisted reproduction, the researchers also constantly improve the technology in order to get better application. So from testing only a finite number of chromosome initially gradually optimized for whole genome screening technology. Embryonic detection method also began to change from invasive to noninvasive method. Many reproductive medicine centers had reported the clinical outcomes of preimplantation genetic testing technology. By comparing the results from different institution, we learn the advantages and limitations of different diagnosis technology, testing technology and the latest technology. Combined with the development process of preimplantation genetic testing technology, this article reviews the current research progress in clinical application of preimplantation genetic testing technology.
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