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Perioperative Risk Factors for Post-operative Pneumonia after Type A Acute Aortic Dissection Surgery

摘要Objective:Type A acute aortic dissection(TAAAD)is a dangerous and complicated condition with a high death rate before hospital treatment.Patients who are fortunate to receive prompt surgical treatment still face high in-hospital mortality.A series of post-operative complications further affects the prognosis.Post-operative pneumonia(POP)also leads to great morbidity and mortality.This study aimed to identify the prevalence as well as the risk factors for POP in TAAAD patients and offer references for clinical decisions to further improve the prognosis of patients who survived the surgical procedure.Methods:The study enrolled 89 TAAAD patients who underwent surgical treatment in Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei province,China from December 2020 to July 2021 and analyzed the perioperative data and outcomes of these patients.Logistic regression analyses were used to identify the risk factors for POP.Results:In the study,31.5%of patients developed POP.Patients with POP had higher proportions of severe oxygenation damage,pneumothorax,reintubation,tracheotomy,renal replacement therapy,arrhythmia,gastrointestinal bleeding,and longer duration of mechanical ventilation,fever,ICU stay,and length of stay(all with P<0.05).The in-hospital mortality was 2.3%.Smoking,preoperative white blood cells,and intraoperative transfusion were the independent risk factors for POP in TAAAD.Conclusion:Patients who underwent TAAAD surgery suffered poorer outcomes when they developed POP.Furthermore,patients with risk factors should be treated with caution.

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作者 Li-juan HUA [1] Lu-xia KONG [2] Jian-nan HU [1] Qian LIU [1] Chen BAO [1] Chao LIU [1] Zi-ling LI [1] Jun CHEN [3] Shu-yun XU [1] 学术成果认领
作者单位 Department of Respiratory and Critical Care Medicine,Key Laboratory of Pulmonary Diseases of Health Ministry,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China [1] Department of Respiratory and Critical Care Medicine,Taikang Tongji(Wuhan)Hospital,Wuhan 430050,China [2] Department of Cardiovascular Surgery,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China [3]
栏目名称 ORIGINAL ARTICLES
DOI 10.1007/s11596-022-2659-4
发布时间 2023-04-03
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