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Pravastatin: A potential cause for acute pancreatitis

摘要Acute pancreatitis (AP) secondary to drugs is uncommon, with an incidence ranging from 0.3% to 2.0%of AP cases. Drug-induced AP due to statins is rare, and only 12 cases have thus far been reported. In this case report, we report a case of a 50-year-old female on pravastatin therapy for 3 d prior to developing symptoms of AP. The common etiological factors for AP were all excluded. The patient was admitted to the intensive care unit secondary to respiratory distress, though she subsequently improved and was discharged 14 d after admission. Although the incidence of drug-induced AP is low, clinicians should have a high index of suspicionfor it in patients with AP due to an unknown etiology.Clinicians should be aware of the association of statins with AP. If a patient taking a statin develops abdominal pain, clinicians should consider the diagnosis of AP and conduct the appropriate laboratory and diagnostic evaluation if indicated.

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作者单位 Department of Internal Medicine, Saint Peter's University Hospital, Robert Wood Johnson Medical School New Brunswick, NJ, United States [1] Division of Gastroenterology, Hepatology and Clinical Nutrition, Department of Internal Medicine, Saint Peter's University Hospital, Robert Wood Johnson Medical School, New Brunswick, NJ, United States [2]
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发布时间 2006-12-18(万方平台首次上网日期,不代表论文的发表时间)
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