摘要AIM: To determine clinical characteristics and treatmentoutcome of gastric lymphoma after chemotherapy and immuno-chemotherapy.METHODS: Thirty four patients with primary gastric mucosa associated lymphoid tissue (MALT) lymphoma (Ann Arbor stages I to IV) were enrolled. All had upper gastric endoscopy, abdominal ultrasonography, CT and H py/or/status assessment (histology and serology).After anti-/-/py/or/treatment and initial chemotherapy,patients were re-examined every 4 mo.RESULTS: Histological regression of the lymphoma wascomplete in 22/34 (64.7%) and partial in 9 (26.5%)patients. Median follow up time for these 31 responders was 60 mo (range 48-120). No regression was noted in 3 patients. Among the 25 (73.5%) H py/or/positive patients, the eradication rate was 100%.CONCLUSION: Using univariate analysis, predictive factors for overall survival were international prognostic index (IPI) score, hemoglobin level, erythrocyte sedimentation rate (ESR), and platelet numbers (P < 0.005). In addition to this, Cox proportion hazard model differentiate IPI score, ESR, and platelets as predictors of survival.