换一批
换一批摘要Apoptosis or programmed cell death (PCD) is an evolutionarily conserved cellular process that is essential for normal development and homeostasis of multicellular organisms. Defects in the apoptosis signaling result in many diseases including autoimmune diseases and cancer. The apoptosis signaling pathway was first described genetically in the nematode Caenorhabditis elegans which serves as a framework for the more complex apop totic pathways that exist in mammals. In this review, we will discuss the apoptotic pathways that are emerging in mammals as elucidated by studies of gene-targeted mutant mice.
更多相关知识
栏目名称
REVIEWS
DOI
10.1038/sj.cr.7290054
发布时间
2004-01-08
- 浏览94
- 被引7
- 下载0
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
