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The Integrator complex controls the termination of transcription at diverse classes of gene targets

作者单位 Department of Pathology, Laura and Isaac Perlmutter Cancer Center, New York University School of Medicine, 522 First Avenue,New York, NY 10016, USA ^[1] HIV Drug Resistance Program, National Cancer Institute, Frederick, MD 21702, USA ^[2] Cancer Research Technology Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA ^[3] The Stowers Institute for Medical Research, Kansas City, MO 6411, USA ^[4] QIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland 4006, Australia ^[5] The Stowers Institute for Medical Research, Kansas City, MO 6411, USA;Department of Pathology and Laboratory Medicine, The University of Kansas Medical Center, Kansas City, KS 66160, USA ^[6]

关键词 Integrator snRNA histone termination RNA Polyermase Ⅱ processing

栏目名称

ORIGINAL ARTICLES

DOI 10.1038/cr.2015.19

发布时间 2015-04-17（万方平台首次上网日期，不代表论文的发表时间）

基金项目

This work was funded by grants from the National Health and Medical Research Council of Australia to KKK and grants from the National Institutes of Health （(R01-GM057587,R37-CA076584,and R21-CA161108)） :JRS is a Special Fellow of The Leukemia & Lymphoma Society,received support from the Mr :and Mrs :William G Campbell Postdoctoral Fellowship in Memory of Carolyn Cabott from the American Cancer Society,and is currently supported by NIH T32 CA009161 (Levy) :A Saraf,L Florens,and MP Washburn are supported by the Stowers Institute for Medical Research :The Hughes laboratory was supported by the Intramural Research Program of the National Institutes of Health,National Cancer Institute,Center for Cancer Research :This project has been funded in part (XW) with Federal funds from the Frederick National Laboratory for Cancer Research,National Institutes of Health,under contract HHSN261200800001E