摘要目的:了解2型糖尿病（T2DM）合并轻度认知障碍（MCI）患者胰岛素笔皮下注射知识的掌握情况及影响因素，以及相关知识的主要需求及来源途径。方法:采用便利抽样法，选取2016年7月—2018年7月首都医科大学附属北京友谊医院收治的132例T2DM合并MCI患者，采用问卷调查的方式收集研究对象的一般资料和对胰岛素笔皮下注射知识的掌握情况、主要需求、来源途径，采用单因素和多重线性回归分析T2DM合并MCI患者胰岛素笔皮下注射相关知识掌握情况的影响因素。结果:T2DM合并MCI患者最希望获得的胰岛素笔注射知识是正确注射方式（81.82%）和注射部位的选择（75.00%）；T2DM合并MCI患者胰岛素笔注射知识的主要来源是社区保健宣传（72.73%）和病友经验介绍（64.39%）。患者糖尿病知识总分为（22.20±5.40）分；单因素分析显示，不同学历、糖尿病病程、家庭人均月收入、胰岛素笔使用时长及是否接受过培训的T2DM合并MCI患者胰岛素笔注射知识掌握情况比较，差异有统计学意义（ P<0.05）；多重线性回归分析显示，学历、糖尿病病程、胰岛素笔使用时长及是否接受过培训是T2DM合并MCI患者胰岛素笔注射知识掌握情况的影响因素（ P<0.05）。 结论:T2DM合并MCI患者的胰岛素笔皮下注射知识相对缺乏，尤其是学历低、糖尿病病程短、胰岛素笔使用时间短及未接受过培训的患者。护理教育者应加强胰岛素注射方式和注射部位等相关知识的教育，并重视社区医院和同伴支持的作用，以满足患者对相关知识的需要。

abstractsObjective:To explore the cognition, needs and source of knowledge of subcutaneous injection with insulin pens in patients with type 2 diabetes mellitus (T2DM) and mild cognitive impairment (MCI) , to analysis the influencing factors of their knowledge level.Methods:Totally 132 T2DM and MCI patients hospitalized in Beijing Friendship Hospital, Capital Medical University from July 2016 to July 2018 were selected using convenient sampling. The questionnaire survey was used to collect the general information of the research subjects and their cognition, needs and source of knowledge of subcutaneous injection with insulin pens. Univariate and multiple linear analysis was used to analyze the factors affecting the knowledge of subcutaneous injection with insulin pens in T2DM and MCI patients.Results:The most desired knowledge of insulin pen injection for T2DM and MCI patients was the correct injection method (81.82%) and the choice of injection site (75.00%) . The main source of insulin pen injection knowledge for T2DM and MCI patients was community health promotion (72.73%) and patient experience sharing (64.39%) . The total score of diabetes knowledge of the patients was (22.20±5.40) . The univariate analysis showed that the knowledge of insulin pen injection was statistically significantly different between T2DM and MCI patients with different educational backgrounds, course of diabetes, monthly household income per capita, duration of insulin pen use, and whether they received training ( P<0.05) . The multiple linear regression analysis revealed that educational background, course of diabetes, duration of insulin pen use and whether they have received training were the influencing factors of the knowledge of insulin pen injection knowledge in T2DM and MCI patients ( P<0.05) . Conclusions:The knowledge of subcutaneous injection with insulin pens in T2DM and MCI patients is relatively lacking, especially in patients with low educational background, short course of diabetes, short duration of insulin pen use and no training. Nursing educators should strengthen the education of relevant knowledge such as insulin injection methods and injection sites, and pay attention to the role of community hospitals and peer support to meet the needs of patients for relevant knowledge.