摘要目的:探讨自我管理干预在慢性肾脏病非透析患者中的应用效果。方法:采用方便抽样的方法，选择2019年1—10月首都医科大学附属北京同仁医院肾内科住院的146例慢性肾脏病非透析患者为研究对象，随机分为对照组（72例）与干预组（74例）。对照组采用常规护理方法，干预组在常规护理的基础上实施自我管理干预。干预6个月后，比较两组患者的BMI、肾病相关负担水平与生活质量水平。结果:干预后，干预组患者BMI正常者占比高于对照组，两组BMI比较差异有统计学意义（χ 2=8.203， P<0.05）；干预组肾病相关负担各维度评分高于对照组，差异均有统计学意义（ t值分别为2.523、2.786、2.648、3.286、2.864、2.445、4.178、3.169、2.351、2.027、2.381； P<0.05）；干预组患者生活质量各维度评分高于对照组，差异均有统计学意义（ t=2.745、4.271、2.766、4.510、2.180、2.622、3.077、3.582； P<0.05）。 结论:自我管理干预可以改善慢性肾脏病非透析患者的营养状况、肾病相关负担水平与生活质量，建议将其应用于临床慢性肾脏病患者的护理中。

abstractsObjective:To explore the effects of self-management intervention in non-dialysis patients with chronic kidney disease.Methods:Totally 146 patients with chronic kidney disease hospitalized in the Department of Nephrology of Beijing Tongren Hospital, Capital Medical University between January and October 2019 were selected by convenient sampling, and divided into a control group ( n=72) and an intervention group ( n=74) . Patients in the control group received conventional nursing care, while patients in the intervention group received self-management intervention on this basis. After 6 months of intervention, the body mass index (BMI) , nephropathy-related burden and quality of life were compared between the two groups of patients. Results:After the intervention, the proportion of patients with normal BMI in the intervention group was higher than that in the control group, and the difference in BMI between the two groups was statistically significant (χ 2=8.203; P<0.05) . The intervention group had higher scores in all dimensions of nephropathy-related burden than the control group, and the differences were statistically significant ( t=2.523, 2.786, 2.648, 3.286, 2.864, 2.445, 4.178, 3.169, 2.351, 2.027, 2.381; P<0.05) . The intervention group had higher quality of life scores than the control group, and the differences were statistically significant ( t=2.745, 4.271, 2.766, 4.510, 2.180, 2.622, 3.077, 3.582; P<0.05) . Conclusions:Self-management intervention can improve the nutritional status, nephropathy-related burden and quality of life of non-dialysis patients with chronic kidney disease, and it is recommended to be used in the care of patients with chronic kidney disease in clinical practice.