摘要目的:检索、评价和总结轻中度帕金森病患者居家运动管理的相关证据，为临床医护人员构建、完善患者居家运动干预方案提供借鉴和参考。方法:按照"6S"证据模型自上而下的原则，系统检索UpToDate、BMJ、英国国家卫生与临床优化研究所、国际指南协作网、美国国立指南网、医脉通、临床指南网、澳大利亚乔安娜布里格斯研究所、Cochrane Library、PubMed、CINAHL、Web of Science、Embase、中国知网、万方、维普网和中国生物医学文献数据库中与帕金森病患者居家运动管理相关的文献，包括指南、专家共识、系统评价、证据总结、临床决策、推荐实践、最佳实践。检索时限为建库至2022年10月31日。由2名研究人员独立对文献质量进行评价及证据提取和整合。结果:共纳入27篇文献，包括3篇指南，5篇专家意见和共识，3篇临床实践建议，15篇系统评价和1篇临床决策。围绕组织管理、健康教育、运动评估、运动处方、家庭及社会支持、监测指导6个方面总结出45条证据。结论:该研究总结了轻中度帕金森病患者居家运动管理的最佳证据，可为临床医护人员制定居家运动管理方案、规范实践标准提供循证依据。

abstractsObjective:To retrieve, evaluate and summarize relevant evidence on home-based exercise management in patients with mild to moderate Parkinson's disease, so as to provide reference and guidance for clinical healthcare professionals to construct and improve patient home-based exercise intervention plans.Methods:According to the top-down principle of the "6S" evidence model, UpToDate, BMJ, National Institute for Health and Clinical Excellence, Guidelines International Network, National Guideline Clearinghouse, Medlive, Clinical Guidelines Network, Joanna Briggs Institute, Cochrane Library, PubMed, CINAHL, Web of Science, Embase, China National Knowledge Infrastructure, Wanfang Data, VIP and China Biology Medicine Disc were systematically searched for relevant literature on home-based exercise management in patients with Parkinson's disease, including guidelines, expert consensuses, systematic reviews, evidence summaries, clinical decisions, recommended practices and best practices. The search period was from the establishment of the databases to October 31, 2022. Two researchers independently evaluated the quality of the literature and extracted and integrated evidence.Results:A total of 27 articles were included, including three guidelines, five expert opinions and consensuses, three clinical practice suggestions, 15 systematic evaluations and one clinical decision. A total of 45 pieces of evidence were summarized from six aspects, such as organizational management, health education, exercise evaluation, exercise prescription, family and social support and monitoring guidance.Conclusions:This study summarized the best evidence of home-based exercise management for patients with mild to moderate Parkinson's disease, which can provide evidence-based basis for clinical staff to formulate home-based exercise management programs and standardize practice standards.