摘要目的:构建衡量护士经外周静脉置入中心静脉导管（PICC）相关性血栓预防的知识、态度和行为水平的评价工具。方法:2022年12月—2023年4月，以知信行理论为框架，通过系统文献回顾、2轮德尔菲专家函询、预调查形成护士PICC相关性血栓预防知信行问卷初稿。2023年5月，采用便利抽样法，选取中国医学科学院北京协和医院的573名护士为研究对象进行调查，对问卷进行项目分析、效度检验和信度检验。结果:最终版护士PICC相关性血栓预防知信行问卷包括知识维度20个条目、态度维度10个条目、行为维度10个条目。问卷的内容效度中的平均内容效度指数为0.984、全体一致内容效度指数为0.850、条目水平的内容效度指数为0.857～1.000；探索性因子分析提取出特征值>1.000的公因子3个，累积方差贡献率为64.540%，各条目因子载荷为0.450～0.908。问卷总的Cronbach's α系数为0.895，折半信度系数为0.947，重测信度系数为0.966。结论:本研究构建的护士PICC相关性血栓预防知信行问卷具有良好的信效度，可作为评估护士PICC相关性血栓预防知识、态度、行为的工具。

abstractsObjective:To construct a tool to evaluate the knowledge, attitude, and practice of nurses in the prevention of thrombosis related to peripherally inserted central catheter (PICC) .Methods:From December 2022 to April 2023, based on the theory of knowledge, attitude, and practice, a preliminary draft of the PICC-related Thrombosis Prevention Knowledge, Attitude, and Practice Questionnaire for Nurses was formed through systematic literature review, two rounds of Delphi expert consultations, and pre-survey. In May 2023, convenience sampling was used to select 573 nurses from Chinese Academy of Medical Sciences & Peking Union Medical College Hospital as the research subject for a survey to conduct item analysis, validity testing, and reliability testing on the questionnaire.Results:The final version of the PICC-related Thrombosis Prevention Knowledge, Attitude, and Practice Questionnaire for Nurses included 20 knowledge items, 10 attitude items, and 10 practice items. In the content validity of the questionnaire, the average content validity index was 0.984, the overall consensus content validity index was 0.850, and the item level content validity index was 0.857 to 1.000. Exploratory factor analysis extracted three common factors with eigenvalues>1.000, with a cumulative variance contribution rate of 64.540% and factor loadings of 0.450 to 0.908 for each item. The total Cronbach's α coefficient of the questionnaire was 0.895, the half reliability coefficient was 0.947, and the retest reliability coefficient was 0.966.Conclusions:The PICC-related Thrombosis Prevention Knowledge, Attitude, and Practice Questionnaire for Nurses has good reliability and validity, and can be used to evaluate PICC-related thrombosis prevention knowledge, attitude, and practice among nurses.