摘要目的:检索、评价并总结老年人便秘非处方药物应用管理的相关证据，为促进老年人便秘非处方药物合理应用提供循证依据。方法:系统检索计算机决策支持系统、指南网站、相关专业协会网站以及数据库中关于老年人便秘非处方药物应用管理的临床决策、指南、证据总结和专家共识。检索时限为2018年1月—2023年3月，对文献进行独立质量评价并提取证据。采用2014版澳大利亚乔安娜布里格斯研究所证据分级系统确定证据等级。结果:共纳入文献18篇，包括临床决策2篇、指南5篇、专家共识7篇和证据总结4篇，围绕不同特点的老年便秘人群的用药原则、药物选择、用药监测、健康教育和注意事项5个方面，共汇总30条最佳证据。结论:本研究总结了老年人便秘非处方药物应用管理的最佳证据，为推动老年人便秘非处方药物合理应用提供了循证依据。

abstractsObjectives:To search, evaluate, and summarize the evidence related to the application management of over-the-counter (OTC) medications for constipation in the elderly, providing evidence-based support for the rational use of these medications.Methods:A systematic search was conducted through computerized decision support systems, guideline websites, professional association websites, and databases for clinical decisions, guidelines, evidence summaries, and expert consensus on the management of OTC medications for constipation in the elderly. The search period spanned from January 2018 to March 2023. The quality of the literature was independently assessed, and evidence was extracted. The 2014 version of the Joanna Briggs Institute (JBI) evidence grading system was used to determine the levels of evidence.Results:A total of 18 article were included, consisting of two clinical decisions, five guidelines, seven expert consensus statements, and four evidence summaries. These covered five areas: medication principles for elderly individuals with different characteristics, medication selection, medication monitoring, health education, and precautions, culminating in a total of 30 best evidence.Conclusions:This study summarizes the best evidence for the management of OTC medications for constipation in the elderly, providing evidence-based support for the rational application of these medications.