摘要目的 比较眼前段光学相干断层扫描仪(AS-OCT)与超声生物显微镜(UBM)测量中央前房深度(ACD)的差异和两者的可重复性.方法 分别用AS-OCT和UBM测量急性原发性闭角型青光眼(APACG)患者29例55眼(发作眼32眼,未发作眼23眼),慢性原发性闭角型青光眼(CPACG)患者4l例74眼的ACD.采用配对t检验进行不同仪器ACD测量值比较;相关分析法分析两种仪器测量值之间的相关性.完全随机法选择1只眼分别用AS-OCT和UBM依次重复测量ACD 10次,比较测量的可重复性.结果 APACG发作眼用AS-OCT测量的ACD值与UBM的测量值之间差异无统计学意义.APACG对侧眼、CPACG眼的AS-OCT测量值比UBM测量值大[(1.923+0.287)mm比(1.860±0.243)mm,(2.017±0.054)mm比(1.913±0.052)mm,均P=0.012].AS-OCT和UBM的ACD测量值呈正相关(r=0.928,P<0.001).AS-OCT与UBM测量ACD的变异系数分别为0.66%和0.82%.结论 AS-OCT比UBM测量的ACD值大,两种仪器测量值相关性良好.AA-OCT的可重复性优于UBM.

abstractsObjective To compare the difference and repeatability between anterior segment optical coherence tomography (AS-OCT) and ultrasound biomicroscope (UBM) in measuring central anterior chamber depth (ACD). Methods Twenty-nine patients (32 attacked eyes and 23 unaffected fellow eyes) with acute primary angle closure glaucoma (APACG) and 41 patients (74 eyes) with chronic primary angle closure glaucoma (CPACG) were included in this study. AS-OCT and UBM were used to measure the ACD of these APACG and CPACG subjects. Pair sample t test and correlation analysis were introduced to analyze the difference and correlation of the ACD values between the 2 instruments. ACD of one complete randomly selected eye was measured 10 times by the above 2 instruments, respectively, and the repeatability of 2 instruments was analyzed. Results There was no significant difference in ACD values of attacked eyes of APACG between AS-OCT and UBM. In unaffected fellow eyes and CPACG eyes, the ACD values measured by AS-OCT were deeper than that measured by UBM[ (1.923±0.287) mm vs (1.860±0.243) mm, (2.017±0.054) mm vs (1.913±0.052) mm, both P=0.012]. Positive correlation between AS-OCT and UBM in measuring ACD was found (r=0.928, P<0.001). The coefficient of variation of ACD was 0.66% as measured by AS-OCT, and 0.82% as by UBM. Conclusions The ACD measured by AS-OCT can be deeper than that by UBM. Excellent correlation is found between AS-OCT and UBM measurements. AS-OCT appears to be more repeatable in measuring ACD than UBM.