摘要急性百草枯中毒临床病死率高,无特效解毒剂.除常规治疗外,早期血液净化促进毒物排出、应用糖皮质激素及免疫抑制剂、抗氧化剂防治重要脏器损伤,对非爆发型患者显示出一定疗效,是目前研究热点,但仍无突破性进展.对于严重肺纤维化患者,肺移植有望成为新的希望.
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abstractsParaquat(PQ) poisoning can lead to high fatalities due to the lack of a specific antidote. Besides routine treatment,excretion of PQ through blood purification at early stages and use of glucocorti-coid,immunosuppressant and antioxidant to prevent the important organs injury show effectiveness in the treatment of non-explosive PQ poisoning,which are the focus of current research.However,there is no ground breaking progress.Lung transplantation is becoming a potential therapy for the patients with severe pulmonary fibrosis.
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