摘要Gallbladder cancer is the most common malignancy of biliary tract with a very poor prognosis. The therapeutic strategy of gallbladder cancer has been improved in some aspects. Identifying the accurate stage is the basis of surgical treatment. Radical resection is the only choice of treatment which provides patients long survival. For most patients in T1a stage, simple cholecystectomy is adequate, but dissection of hepatoduodenal ligament should be added when the lesions located in neck and duct of gallbladder. Patients in T1b stage often need radical cholecystectomy. Radical cholecystectomy with Ⅳb and Ⅴ segmentectomy and lymphadenectomy of N2 nodes should be performed to patients in T2 stage. Extended right lobe resection can improve the prognosis of selected T3 and T4 patients.The effect of chemotherapy for gallbladder cancer remains unsatisfactory, and current chemotherapeutic regimens were based on 5-FU, gemcitabine or S-1. The effect of a new chemotherapeutic sensitization scheme with continuous infusion of somatostatin,epirubicin 5-FU/CF and cisplatin is under research, and the preliminary results are promising. Radiation shows some benefits to patients with gallbladder cancer, but its effects are still uncertain.

abstracts@@ 胆囊癌是最常见的胆道恶性肿瘤,约占全部胆道系统肿瘤的2/3,占消化系统恶性肿瘤的第5位.胆囊癌的疗效长期徘徊不前,5年总体生存率为5%.综合治疗依然是胆囊癌治疗的主要方式.随着对胆囊癌浸润、转移途径的了解,外科手术技术及围手术期支持的进步,放、化疗方案的改进,胆囊癌的综合治疗取得了一些进展.