换一批
换一批微RNA-483与消化系统肿瘤关系的研究进展
Advances in the relationship between microRNA-483 and digestive system tumors
摘要微RNA(miRNA)是一种小分子的非编码单链RNA,通过翻译抑制或降解信使RNA在转录后水平调节基因表达.miRNA参与调节细胞的多种生物学过程,其表达水平的异常与肿瘤的发生密切相关.miR-483参与多种肿瘤的发生及演变,而其在消化系统肿瘤中的作用已引起广泛关注.
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abstractsMicroRNA (miRNA) is a kind of small non-coding RNA that regulates gene expression at the posttranscriptional level through inhibition of translation or degradation of messenger RNA.MiRNA is involved in the regulation of many cellular biological processes,and its abnormal expression closely relates to development of tumors.MiR-483 plays an important role in the tumorgenesis or development,meanwhile,its role in digestive system tumors has aroused widespread attention.
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关键词
胃肿瘤食管肿瘤肝肿瘤消化系统肿瘤微RNA微RNA-483Gastric neoplamsEsophageal neoplasmsHepatic neopalmsDigestive system neoplamsMicroRNAMicro RNA-483
主题词
消化系统肿瘤(Digestive System Neoplasms)研究(Research)胃肿瘤(Stomach Neoplasms)食管肿瘤(Esophageal Neoplasms)肝肿瘤(Liver Neoplasms)
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综述
DOI
10.3760/cma.j.issn.1673-9752.2018.05.019
发布时间
2018-06-19
基金项目
National Natural Science Foundation of China (81171923)国家自然科学基金
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