摘要Civets are small mammals belonging to the family Viverridae.The masked palm civets(Paguma larvata)served as an intermediate host in the bat-to-human transmission of severe acute respiratory syn-drome coronavirus(SARS-CoV)in 2003(Guan et al.,2003).Because of their unique role in the SARS outbreak,civets were suspected as a potential intermediate host of SARS-CoV-2,the etiological pathogen of the Coronavirus disease 2019(COVID-19)pandemic(Wu et al.,2020).In addition to their susceptibility to coronaviruses,civets can also be infected by other viruses,such as canine distemper viruses(Techangamsuwan et al.,2015),parvoviruses(Mendenhall et al.,2016),and influenza viruses(Roberton et al.,2006).Regarding the ecological and economical role of civets,it is vital to evaluate the po-tential threats from different pathogens to these animals.Receptor binding is a necessary step for virus entry into host cells.Understand-ing the distribution of receptors of various viruses provides hints to their potential tissue tropisms.Here,we characterize the cell atlas of five important organs(the frontal lobe,lung,liver,spleen,and kid-ney)of masked palm civets(Paguma larvata)and described the expression profiles of receptor associated genes of 132 viruses from 25 families(Zhang et al.,2019),including 16 viruses from 10 families reported before that can attack civets and 116 viruses with little infection record.