Variants within KIF5B are associated with weight loss through mitochondrial transport alteration in sheep

导出学术成果认领

摘要Sheep(Ovis aries)is a key source of meat for humans,and their weight loss significantly impacts meat production.Although a few causative genes related to weight loss have been identified,the in-heritance mechanisms and genetic pathways involved remain to be further elucidated.Artificial selection can effectively fix substantial mutations in these genes,enhancing meat production in sheep.

作者 Jieran Chen ^[1] Haitao Wang ^[2] Tingting Li ^[2] Yuting Zhang ^[2] Yan Chen ^[2] Na Zhang ^[2] Hengqian Yang ^[2] Zhichao Zhang ^[2] Ziyuan Duan ^[2] Xia Li ^[2] Daxiang Wang ^[3] Zhixiong He ^[4] Fan Hu ^[4] Jianfeng Gao ^[5] Runlin Z.Ma ^[2] Xun Huang ^[2] Qiuyue Liu ^[2] 学术成果认领

作者单位 College of Life Sciences,Shihezi University,Shihezi,Xinjiang 832000,China;State Key Laboratory of Molecular Developmental Biology,Institute of Genetics and Developmental Biology,Chinese Academy of Sciences,Beijing 100101,China ^[1] State Key Laboratory of Molecular Developmental Biology,Institute of Genetics and Developmental Biology,Chinese Academy of Sciences,Beijing 100101,China ^[2] Jiangsu Qianbao Animal Husbandry Co.,Ltd,Yancheng,Jiangsu 224050,China ^[3] CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region,National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production,Hunan;Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process,Institute of Subtropical Agriculture,Chinese Academy of Sciences,Changsha,Hunan 410125,China ^[4] College of Life Sciences,Shihezi University,Shihezi,Xinjiang 832000,China ^[5]

栏目名称 Research Communications

DOI 10.1016/j.jgg.2024.09.009

发布时间 2025-01-08

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