摘要Purposes:To observe the characteristics of local electroretinogram (LERG) in normal subjects and patients with macuiopathies,and to evaluate the applied worth of LERG and pattern visual evoked potential (PVEP) in maculopathies.Methods:LERGs at 5° and 15° macular regions were recorded from 27 normal subjects (54 eyes).The factors of age,different eyes and stimulate areas for LERG influence were observed.Meanwhile,the LERG and PVEP were recorded from 25 patients (35 eyes) with maculopathies for making contrast study.Results:In normal subjects,there was no significant influence of age to LERG.As the stimulated areas increased,the a-and b-wave amplitudes of LERG in-creased.In the patients with maculopathies,the a-and b-wave amplitudes of LERG at 5°,10° and 15° macular regions were significantly lowered and the mean values of P1 latency were prolonged and N1-P1 amplitudes of VEP were lowered,comparing with the control group.In the nearing stimulated area (5° LFRG and 14.9× 19° PVEP),there were no significant differences of the abnormal rates of both LERG and PVEP.Conclusion:There are close sensitivities of testing the function of macular region with LERG and PVEP in maculopathies.However,LERG is not influenced by the visual path diseases and visual acuity,it is a more effective and direct way than PVEP in measuring macular function.