摘要Purpose:.To investigate the genotyping of Foxp3-3279 (A /C,rs376158) genes in patients with dust mite-induced allergic conjunctivitis from Guangdong province and to explore the association between these genes and the susceptibility to dust mite allergic conjunctivitis.Methods:.In total,.80 patients with dust mite allergic con-junctivitis and 103 healthy Han Chinese were enrolled in the study and received genotyping of Foxp3-3279 (A/C,rs376158) by PCR-SSP technique.Results: Genotype frequency of Foxp3-3279 AA,.CA,.and CC in patients with dust mite allergic conjunctivitis were 1.25% , 25.00% and 73.75%,respectively. Gene frequency of C and A in patients with dust mite allergic conjunctivitis were 86.25%and 13.75% with no significant difference from healthy coun-terparts (both P>0.05).Conclusion:.Foxp3-3279 polymorphisms did not significantly differ between patients with dust mite allergic conjunctivitis and healthy controls, implying that this genetic locus is prob-ably not an independent risk factor of the underlying patho-genesis of dust mite allergic conjunctivitis. (Eye Science 2014; 29:151-154)