摘要过敏性角结膜炎是临床常见过敏性疾病,但在临床工作中仍见到一些病例特别是儿童不能得到及时正确的诊治.过敏性角结膜炎主要由Ⅰ型和Ⅳ型变态反应引起,其治疗以局部用药为主.目前临床常用的治疗过敏性角结膜炎抗过敏药包括抗组胺药、肥大细胞稳定剂、双效抗过敏药物、非甾体抗炎药、糖皮质激素及免疫抑制剂.了解各抗过敏药物的作用机制,并根据变态反应的类型选择不同的药物组合对于临床合理治疗过敏性角结膜炎至关重要.临床医师需重视基于过敏性角结膜炎的发病机制选择不同药物的原则,逐步规范用药方案,提高药物疗效.

abstractsAllergic keratoconjunctivitis is a common allergic disease,but some patients,especially children,cannot be diagnosed and treated timely and correctly.Allergic keratoconjunctivitis is mainly caused by type Ⅰ and Ⅳ allergy,and its treatment is mainly based on topical administration.At present,antiallergic drugs used for the treatment of allergic keratoconjunctivitis include Histamine antagonists,mast cell stabilizers,double effect antiallergic drugs,Nonsteroidal anti-inflammatory drugs,glucocorticoids and immunosuppressants.It is essential to understand the mechanism of various antiallergic drugs and to choose different combinations according to the type of allergy to treat allergic keratoconjunctivitis.Clinicians should pay attention to the principle of choosing different drugs based on the pathogenesis of allergic keratoconjunctivitis,gradually standardize the drug regimen and improve the efficacy of drugs.