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Effect of Western medicine therapy assisted byGinkgo biloba tablet on vascular cognitive impairment of none dementia

摘要Objective:To discuss the clinical effects ofWestern medicine therapy assisted byGinkgo biloba tablet(GBT) on patients with vascular cognitive impairment of none dementia(VCIND).Methods:A total of80 patients withVCIND were divided into two groups randomly:Conventional treatment group(control group) and combined treatment group.Conventional treatment group was given conventional treatment with anti-platelet aggregation.In this group,75 mg aspirin was given three times a day for3 months.While in combined treatment group,19.2 mgGBT was given three times a day for3 months together with conventional treatment(anti-platelet aggregation drugs). Montreal cognitive assessment(MoCA) and transcranialDoppler(TCD) were used to observe changes of cognitive ability and cerebral blood flow inVCIND patients before and after treatment in both groups.Then the clinical data were analyzed so as to compare the efficacy in two groups. Results:After3 month-treatment in combined treatment group, the scores of executive ability, attention, abstract, delayed memory, orientation in theMoCA were significantly increased compared with those before treatment and those in control group after treatment.Besides, blood flow velocity of anterior cerebral artery increased significantly than that before treatment and that in control group after treatment.Conclusions:GBT tablet can improve the therapeutic efficacy as well improve cognitive ability and cerebral blood flow supply of patients withVCIND.

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作者单位 Department of Traditional Chinese Medicine, People's Hospital of Zhengzhou, Zhengzhou, Henan Province, 450003, China [1] Department of Neurology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, 450000, China [2]
DOI 10.1016/S1995-7645(12)60135-7
发布时间 2015-12-01
基金项目
National 'Eleventh Five-year Plan' Science and Technology Support Project
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