摘要Objective: To determine post-discharge mortality and associated factors of the first-wave multicenter Turkish Thoracic Society (TTD)-TURCOVID study. Methods: In this retrospective cohort study, we analyzed the data of 18 of 26 centers included in the first TTD-TURCOVID study, and 1112 cases diagnosed with COVID-19 between 11 March and 31 July 2020 participated in the study. All causes of death after COVID-19 discharge were recorded. Results: The mean age of the patients was (51.07±16.93) years, with 57.6％ male patients. In the cohort group, 89.1％ of COVID-19 treatment locations were hospital wards, 3.6％ were intensive care units (ICUs), and 7.2％ were community outpatients. In the long-term follow-up, the in-hospital mortality rate was 3.6％ (95％ CI 2.6-4.8), the post-discharge mortality rate was 2.8％ (95％ CI 1.9-3.9), and the total mortality was 6.3％ (95％ CI 5.0-7.8). After discharge, 63.3％ of mortality overall occurred during the first six months. Mortality rates in post-discharge follow-ups were 12.7％ (95％ CI 8.0-30.6) in cancer patients, 10.8％ (95％ CI 6.3-22.9) in chronic obstructive pulmonary disease patients, 11.1％ (95％ CI 4.4-22.7) in heart failure patients, 7.8 (95％ CI 3.8-14.3) in atherosclerotic heart disease patients, and 2.3％ (95％ CI 0.8-5.6) in diabetes mellitus patients. In smokers/ex-smokers, the all-mortality rates were higher than in non-smokers. Conclusions: This multicenter study showed that patients over 65 years of age, males, former/active smoker, ICU stay, lung, heart disease, and malignancy should be followed up for at least the first six months after discharge due to COVID-19.