摘要目的:建立鸡形觉剥夺近视模型，观察形觉剥夺眼屈光、巩膜形态学改变。 方法:将孵出后一天的家鸡25只，以右眼为形觉剥夺眼，左眼为开放对照眼，2周后进行检影验光，并摘出眼球，测量眼轴长和赤道径。观察巩膜软骨层中细胞密度、增殖细胞率，并测量角巩膜的干湿重。结果:剥夺眼的屈光度平均为-11.9±4.6D,对照眼平均为+3.0±1.2D，两者差异有显著性意义，轴长较对照眼明显延长（P<0.01）,剥夺眼的巩膜干湿重均明显重于对照眼（P<0.01），并且巩膜软骨中增殖细胞率明显高于对照眼（P<0.05），但细胞密度则低于对照眼（P<0.05）。结论：鸡眼形觉剥夺可产生一定程度的近视和眼轴延长，并伴随着巩膜的病理形态改变。

abstractsObjective：To establish the model of form-deprivation myopia in chick, and observe the changes of refractive state and morphology of sclera in deprived eyes.Methods：All the right eyes of twenty-five domestic chicks 1 day after birth underwent form-deprivation with translucent goggles, and the left eyes were used as control. Two weeks later, data including refractive state,eye size,etc were obtained and analyzed.Results：Average refractive value of occluded eyes and control eyes were -11.9±4.6D and 3.0±1.2D respectively. Axial length of occluded eyes was notably longer compared with that in the control(P<0.01). Both wet and dry weight of occluded eye's sclera is heavier than those of control eyes(P<0.01). Conclusion：Form-deprivation could cause myopia and scleral change in chick eye.