摘要目的 分析非球面多焦点人工晶状体(MIOL)[ReSTOR MIOL(SN6AD3)]植入眼在不同背景亮度不同对比度下的视功能.方法 采用前瞻性研究.2009年2月至2009年7月行白内障超声乳化吸除并植入SN6AD3且随访资料完整的病例26例(42眼),术后6个月在最佳远矫正状态下,采用多功能电子视力测量仪(MFVA-100)测试不同背景亮度(250、85、25 cd/m2)下不同对比度(100%、25%、10%、5%)视标的LogMAR视力.采用Dunnett's T3多重比较法对所得视力进行统计分析.结果 在250 cd/m2背景亮度下,不同对比度(100%、25%、10%、5%)视力平均值分别为0.01、0.23、0.40、0.62;85 cd/m2背景亮度下为0.02、0.26、0.46、0.74;25 cd/m2背景亮度下为0.08、0.32、0.49、0.63;在这3种背景亮度下,视力随着对比度下降而下降,差异有统计学意义(P均＜0.05).同一对比度视标,不同背景亮度(250、85、25 cd/m2)下的视力采用Dunnett's T3多重比较法分析,结果示差异无统计学意义(P均＞0.05).结论 植入非球面ReSTOR MIOL(SN6AD3)患者无论在高亮(250 cd/m2)、标准(85 cd/m2)、中间(25 cd/m2)背景亮度下均可获得满意的视力.视标的对比度对视力的影响较背景亮度更大.

abstractsObjective To evaluate the differences in contrast visual acuity (VA) under different background illuminations in patients who had been implanted with the ReSTOR aspheric multifocal intraocular lens (MIOL)(SN6AD3). Methods This was a prospective study. Forty-two eyes of 26 patients who had received ReSTOR MIOL (SN6AD3) implantation after cataract extraction were enrolled. Six months postoperatively, best corrected distance VA was measured at 4 contrast levels (100%, 25%, 10%, 5%) under 3 background illumination levels (250 cd/m2, 85 cd/m2, 25 cd/m2)using a multi-functional visual acuity tester (MFVA-100). Dunnett's T3 multiple comparison was used for statistical anaylysis. Results The mean VA at the 4 contrast levels (100%, 25%, 10%, 5%)under 250 cd/m2 background illumination were 0.01, 0.23, 0.40 and 0.62; under 85 cd/m2, the mean VA were 0.02, 0.26, 0.46 and 0.74; under 25 cd/m2, the mean VA were 0.08, 0.32, 0.49 and 0.63. At the same background illumination level, there was a statistically significant decrease in VA with a decrease in contrast level (P＜0.05). While at the same contrast level, there were no statistically significant differences in VA at different background illuminations (250 cd/m2, 85 cd/m2,25 cd/m2)(P＞0.05). Conclusion Implantation of the ReSTOR MIOL (SN6AD3) offers excellent VA under high luminance (250 cd/m2), normal luminance (85 cd/m2) and moderate luminance (25 cd/m2).VA is affected much more by the contrast of the visual target rather than background illumination.