摘要目的:评价Nd∶YAG激光周边虹膜切除术(LPI)对视觉质量的早期影响.方法:前瞻陛自身对照研究.利用双通道视觉质量分析系统检测2016年3-6月在北京协和医院眼科行LPI的患者在LPI前和1周后的客观散射指数(OSI)、调制传递函数截止频率(MTF cut-off)、斯特列尔比(SR)、客观对比度视力、平均客观散射指数(mean OSI)以及调节力.对LPI治疗前后各参数进行配对t检验和秩和检验分析.结果:共42例(52眼)患者接受LPI,年龄41～ 80岁,平均(63.5±8A)岁.LPI前与LPI治疗1周后视力、眼压比较差异无统计学意义;100％、20％和9％对比度视力在LPI前分别为0.73±0.37、0.49±0.25和0.29±0.13,LPI治疗1周后分别为0.77±0.30、0.54±0.26和0.32±0.15,LPI治疗前后差异无统计学意义;LPI前与LPI治疗1周后OSI、MTF cut off、SR、mean OSI以及调节力比较差异均无统计学意义.结论:Nd∶YAGLPI对早期视觉质量、调节力等均无明显影响,是预防性治疗原发性前房角关闭安全、有效的方法.

abstractsObjective:To evaluate the early impact of Nd∶YAG laser peripheral iridectomy (LPI) on visual quality.Methods:This was a prospective self-controlled study in which patients with primary angle closure underwent LPI during March to June 2016 at Department of Ophthalmology,Peking Union Medical College Hospital were enrolled.An optical quality analysis system was used before and one week after LPI to assess the visual quality.The objective scatter index (OSI),Strehl ratio (SR),modulation transfer function (MTF) cut off,mean OSI,visual acuity (VA)100％,VA 20 ％,and VA 9％,and accommodation values were measured.Differences in the measurements before and one week after LPI were compared by paired t-tests and Wilcoxon rank sum tests.Results:Forty-two patients (52 consecutive eyes,mean age:63.5±8.4,age range 41 to 80 years) received LPI.There were no statistically significant differences in best corrected visual acuity or intmocular pressure before and one week after LPI.VA100％,VA 20％,and VA 9％ before LPI were 0.73±0.37,0.49±0.25,and 0.29±0.13 respectively.At one week after LPI,they were 0.77±0.30,0.54±0.26,0.32±0.15 respectively,with no significant differences from the pre-LPI values.None of the differences in OSI,MTF cut off,SR,mean OSI,and accommodation values before and one week after LPI were all not statistically significant.Conclusions:Nd∶YAG did not have any impact on visual quality or accommodation.LPI was a safe and effective preventive therapeutic procedure for primary angle closure.