摘要白内障是目前最主要的致盲性眼病，临床上通常采用超声乳化联合人工晶状体（IOL）植入对其进行治疗。该手术术后视力恢复良好。但是所植入的IOL是一种外来性异物，术后除了急性炎症反应之外，存在着远期的体内生物相容性问题，即后发性白内障，严重影响术后的视觉质量。虽然手术方式改进、IOL设计加工改良等能降低后发性白内障的发生率，但由于材料本身的相容性问题并未获得改善，仍能导致后发性白内障的发生。笔者从材料学的角度对材料表面性能改性抑制后发性白内障作一综述。

abstractsCataract is the main cause of blinding diseases. Phacoemulsification combined with intraocular lens (IOL) implantation is a commonly used clinical treatment. Visual acuity recovers well after the operation. However, since the IOL is an extrinsic implant, a high incidence of complications may occur postoperatively. In addition to acute inflammation, long-term in vivo biocompatibility problems-posterior capsular opacification (PCO, which is also called a secondary cataract) may occur over time and decrease vision again. The improvement of surgical methods and the design and processing of the IOL can reduce the incidence of PCO. However, PCO still occurs due to the intrinsic compatibility of the IOL materials. This review summarizes the IOL surface modifications used to inhibit PCO from the perspective of the science of materials.