摘要目的 总结主动脉窦瘤破裂合并感染性心内膜炎的易感因素及治疗经验.方法 对2000年1月至2008年3月收治的30例主动脉窦瘤破裂中10例合并感染性心内膜炎的患者的临床资料进行回顾性分析.9例手术治疗,其中6例同时行主动脉瓣替换术.结果 9例行手术治疗患者均康复出院.随访2个月至8年,心功能恢复到Ⅰ级7例,Ⅱ级2例.死亡1例系未行手术治疗者,死于多脏器功能衰竭.结论 合并室间隔缺损是主动脉窦瘤破裂易感因素之一;主动脉窦瘤破裂合并感染性心内膜炎一经确诊,应足量有效抗炎治疗并尽早手术;合并中度以上主动脉瓣关闭不全应果断换瓣治疗.

abstractsObjective To summarize the susceptible factors and the experience of the surgical treatment of ruptured aneurysm of the sinus of Valsalva combined with infective endecarditis.Methods From January 2000 to March 2008,30 cases with raptured aneurysm of the sinus of Valsalva were admitted, clinical data of 10 cases combined with infective endocarditis were retrospectively reviewed.Nine cases underwent the surgical treatment,including 6 cases accepted aortic valve replacement (AVR).Results Nine eases underwent the surgical treatment followed up for 2 months to 8 years,cardiac function of the survivors recovered to Class Ⅰ-Ⅱ in NYHA,7 cases were Ⅰ grade,2 cases were Ⅱ grade.One case was dead for MSOF not underwent the surgical treatment.Conclusions Associated with ventricular septal defect is one of the susceptible factors.Following diagnosis of ruptured aneurysm of sinus of Valsalva combined with infective endocarditis,sufficiently and validly antibiotic and surgical treatment should be pedormed as quickly as possible,and AVR to the moderate and severe aortic insufficiency.