摘要目的 研究外伤性迟发性颅内血肿(DTIH)患者外周血中自细胞及中性粒细胞的变化,并探讨其临床意义.方法 收集2005年6月至2007年12月急诊收治的116例DTIH患者和123例非DTIH患者的外周血,检测外周血中白细胞及中性粒细胞计数并分组进行对比.结果 首次头颅CT检查无颅内血肿,再次检查发现颅内血肿的DTIH患者入院时外周血中白细胞计数(13.35±6.72)×109/L及中性粒细胞计数(12.78±6.43)×109/L,明显高于首次及多次头颅CT检查均未见颅内血肿患者[白细胞计数(9.72±3.09)×109/L及中性粒细胞计数(7.64±2.93)×109/L],差异有统计学意义(P＜0.01);而首次头颅CT检查即发现颅内血肿的DTIH患者和非DTIH患者人院时外周血中自细胞及中性粒细胞计数差异无统计学意义(P＞0.05).结论 白细胞及中性粒细胞计数可以作为一项客观指标协助首次头颅CT检查无颅内血肿的DTIH患者的早期诊断.

abstractsObjective To investigate the clinical significance of leukocyte count and neutrophil count change on delayed traumatic intracranial hemorrhage(DTIH).Method Collected the peripheral venous blood of l 16 eases of DTIH and 123 cases of non-DTIH between June 2005 and Deeember 2007.Compared the leukocyte count and neutrophil count in all cases by different groups.Results The leukocyte count and neutrophil count of the DTIH patients whose first CT scan were negative[(13.35±6.72)×109/Land(12.78±6.43)×109/L,respectively]were significantly higher than those of head injury whose CT scan werenegative allthetime[(9.72±3.09)×109/Land(7.64±2.93)×109/L,respectively].The difference was significant (P＜0.01).There were no statistical significance of the leukocyte count and neutrophil count between DTIH patients and non-DTIH patients whose first CT scan were positive(P＞0.05).Conclusions As an independent guideline,the leukocyte count and neutrophil count may help the forepart diagnosis of DTIH patients whose first CT scan were negative.