摘要目的 研究可能影响长期腹膜透析患者生存质量的非医疗因素,旨在为临床工作中如何提高患者的生存质量提供依据.方法 采用横断面研究方法调查79例慢性肾衰竭进行持续非卧床腹膜透析(CAPD)患者.记录患者的年龄、性别、工作状况、文化程度、医疗负担及家庭支持等情况.采用国际通用的KDQOL-SFTM1.2中的短表SF-36评估患者的生存质量.采用汉密尔顿焦虑抑郁量表评估患者的焦虑、抑郁指数.结果 SF-36评估患者的生存质量提示:CAPD患者生存质量的8个方面得分均显著低于中国一般人群(P＜0.05或＜0.01);在职患者和有医疗保障患者SF-36得分分别为(45.78±16.93)分和(49.62±13.20)分,明显高于非在职患者的(32.65±12.26)分和无医疗保障患者的(33.85±6.24)分(P＜0.05);人均年收入越高的家庭,患者生存质量就越高;有子女和老伴共同照顾的患者生存质量最高,而由保姆或个人照顾的患者生存质量最低;79例患者中焦虑的发生率为54.4%(43/79),抑郁的发生率为15.2%(12/79),二者均与生存质量呈显著负相关.结论 家庭支持、工作状况、医疗保障和心理障碍均对CAPD患者的生存质量产生重要影响.

abstractsObjective To evaluate the quality of life (QOL) in continuous ambulatory peritoneal dialysis (CAPD) patients and analyze the non-medical factors influencing QOL in order to explore the possible way to improve QOL in peritoneal dialysis (PD) patients.Methods Seventy-nine chronic renal failure patients treated with PD included in the present study.Investigated their age,sex,working status,education,medical burden and family support.Patients' QOL was evaluated by international questionnaire-KDQOL/SF-36.Patients' anxiety/depmssion status was evaluated by Hamilton depression questionnaire.Results (1)The SF-36 with its eight scales of CAPD patients were markedly lower than ordinary people (P＜0.05 or＜0.01).(2) Comparing with those on work,the patients without work got lower SF-36 scores[(45.78±16.93) seores vs (32.65±12.26) scores,P＜0.05].Comparing with those who had medical care,the patients without medical care got much lower SF-36 scores [(49.62±13.20) scores vs (33.85±6.24) scores,P＜0.05].Patients with higher income had better QOL.(3) Patients cared by their children and companion had the higheat SF-36 [(68.33±14.73) scores],while those cared by nursemaid or themselves had the lowest [(27.98±15.77) scores].(4) Among the 79 patients,43 patients (54.4%) were anxiety and 12 patients (15.2%) were depression.QOL was negatively correlated with anxiety index and depression index.Conclusion The QOL of CAPD patients are remarkably low,which is deeply influenced by many non-medical factors such as working status,medical burden,family support and emotional status.