摘要目的 探讨孕妇产后脑后部可逆性脑病综合征(PRES)的MRI影像学特点.方法 回顾性分析8例孕妇产后PRES患者的临床及影像学资料,其中5例为产后1周内发生,2例为产后2周发生,1例为产后4周发生.8例患者均行MRI检查,检查序列包括T1WI、T2WI、FLAIR、弥散加权像(DWI)、磁敏感序列(SWX),其中4例患者行磁共振静脉成像(MRV).结果 8例患者MRI显示脑内病变均呈对称性分布,好发于大脑后部顶枕叶,额叶亦常受累,其他相对少见的病变范围包括脑干、小脑及基底节区等,病变于T1WI呈等或低信号,T2WI及FLAIR呈高信号,部分病灶DWI表现为高信号.其中双侧顶叶8例、双侧枕叶8例、双侧额叶4例、双侧颞叶6例、双侧颞枕叶交界区8例、胼胝体压部1例、双侧基底节区1例、双侧半卵圆中心1例、双侧小脑半球1例,左侧额叶脑出血1例.5例随访MRI显示病灶范围和数目明显变小、减少、消失.结论 MRI可以对孕妇产后PRES做出明确诊断,从而进一步指导临床治疗及预防并发症.

abstractsObjective To investigate the MRI appearances of postpartum posterior reversible encephalopathy syndrome (PRES). Methods The clinical and radiological data of 8 patients with postpartum PRES were analyzed retrospectively, 5 cases were 1 week after postpartum,2 cases were 2 weeks afterpostpartum, 1 case was 4 weeks after postpartum. All cases underwent MRI examination, checking sequence included T,WI,T2WI,FLAIR,DWI,SWI, and 4 of them underwent MR venography (MRV). Results MRI showed basal bilaterally symmetrical distributions of lesions, mainly located in subcortex and cortex of cerebral hemisphere and predominantly in the occipital lobe,the lesions appeared as hyperintensity on FLAIR and T2WI,isointensity or mildly hypointensity on T1WI,hyperintensity on DWI. MRI in 8 patients demonstrated multiple lesions located in bilateral parietal lobe (8 cases),bilateral occipital lobe (8 cases), bilateral frontal lobe ( 4 cases ), bilateral temporal lobe (6 cases ), bilateral tempura-occipital lobe ( 8 cases),splenium of corpus callosum(l case), bilateral basal ganglia (l case), bilateral oval center( 1 case), bilateral cerebellar hemisphere (1 case), left frontal lobe hemorrhage (l case). Five patients' follow-up scan showed decreased or disappeared abnormal signals. Conclusion MRI examination scan identify the location, quality and degree, meanwhile, analyze the pathological foundation of postpartum PRES, which conduces to guiding treatment and preventing complication.