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腹腔镜下卵巢囊肿剥除术不同止血方法对卵巢功能影响的对照研究

Control study on influence of different hemostatic measures of laparoscopic ovarian cyst removed on ovarian function

摘要目的 探讨腹腔镜下卵巢囊肿剥除术不同止血方法对卵巢功能的影响.方法 将70例卵巢囊肿患者按机械抽样法随机分为Ⅰ组(23例)和Ⅱ组(47例),均择期行腹腔镜下卵巢囊肿剥除术,Ⅰ组患者术中止血采取电凝法,Ⅱ组患者采取缝合法.比较两组术前及术后6个月雌二醇、卵泡刺激素(FSH)、黄体生成激素(LH)、窦状卵泡数、卵巢功能正常例数及卵巢储备功能下降例数.结果 术后Ⅱ组卵巢功能正常率明显高于Ⅰ组[ 80.9%( 38/47)比39.1%(9/23)](P<0.05),雌二醇和窦状卵泡数显著高于Ⅰ组[(198.4±24.4) pmol/L比(153.4±16.8) pmol/L,(7.1±2.4)个比(5.8±0.9)个](P<0.05),而FSH和FSH/LH显著低于Ⅰ组[(10.58±4.57) U/L比(13.72±2.58) U/L,2.34±1.32比2.82±0.88](P<0.05).结论 腹腔镜下卵巢囊肿剥除术时,采用电凝止血会显著降低残留卵巢功能,而采用缝合法止血可有效保护卵巢功能.

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abstractsObjective To explore the influence of different hemostatic measures of laparoscopic ovarian cyst removed on ovarian function.Methods Seventy patients with ovarian cyst who performed laparoscopic ovarian cysts removed between January 2009 and December 2010 were randomly divided into group Ⅰ (23 cases) and group Ⅱ (47 cases) by mechanical sampling.Group Ⅰ with bleeding electrocautery,group Ⅱ with suture.Estradiol,follicle puncture hormone (FSH),luteinizing hormone (LH),number of sinusoidal follicles,normal ovarian function and the number of declining ovarian reserve were compared in two groups before operation and after 6 months operation.Results After operation,the proportion of group Ⅱ with normal ovarian function was significantly higher than that of group Ⅰ [80.9%(38/47) vs.39.1%(9/23),P < 0.05 ],estradiol and number of sinusoidal follicles were significantly higher than those of group Ⅰ [( 198.4 ± 24.4) pmol/L vs.( 153.4 ± 16.8) pmol/L,7.1 ± 2.4 vs.5.8 ± 0.9](P< 0.05),FSH and FSH/LH were significantly lower than those of group Ⅰ [ ( 10.58 ± 4.57) U/L vs. ( 13.72 ± 2.58) U/L,2.34 ± 1.32 vs.2.82 ± 0.88 ] (P < 0.05).Conclusion During laparoscopic ovarian cyst removed,using electrocautery can significantly reduce residual ovarian function,but using suture hemostasis can effectively protect residual ovarian function.

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DOI 10.3760/cma.j.issn.1673-4904.2012.03.011
发布时间 2012-04-20(万方平台首次上网日期,不代表论文的发表时间)
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