摘要目的 评价不采用化疗药物膀胱灌注治疗腺性膀胱炎的治疗效果.方法 对54例未采用化疗药物膀胱灌注的腺性膀胱炎患者的治疗情况和治疗后随访情况进行回顾性分析.结果 病例均获2.5~9.0年随访,平均4.6年.下尿路症状评分在治疗前和治疗后3个月、6个月、2年、4年分别为(8.5 ± 3.7)、(5.7 ± 2.3)、(3.9 ± 1.3)、(4.0 ± 1.9)、(4.2 ± 1.9)分,治疗后的症状评分较治疗前均明显改善,差异有统计学意义(P＜0.05).膀胱镜检查随访第3个月复发率为3.7%(2/54),第6个月复发率为13.0%(7/54),第2年复发率为5.6%(3/54),第4年复发率为1.9% (1/54).随访期间病理结果证实无一例癌变.结论 对于腺性膀胱炎的治疗以去除诱因、改善下尿路症状为主,可以获得满意的治疗效果,不建议采取术后化疗药物膀胱灌注.

abstractsObjective To evaluate the treatment effect of bladder instillation chemotherapy on glandular cystitis. Methods The clinical data of glandular cystitis of 54 cases were retrospectively analyzed, all cases were treated individually and the applications of chemotherapeutic drugs bladder instillation were not adopted. Results Follow-up period ranged from 2.5 to 9.0 years, and the average was 4.6 years. Lower urinary tract symptoms score before treatment, 3 month , 6 month, 2 years , 4 years after treatment was (8.5 ± 3.7), (5.7 ± 2.3), (3.9 ± 1.3), (4.0 ± 1.9), (4.2 ± 1.9) scores, and the scores after treatment were improved significantly compared with that before treatment (P < 0.05). Recurrence rate 3 months , 6 months, 2 years and 4 years after treatment was 3.7%(2/54), 13.0%(7/54), 5.6%(3/54) and 1.9% (1/54). Conclusions Eliminating the inducements and improvement of symptoms provides a significantly curative effect in glandular cystitis. Postoperative bladder instillation chemotherapy is not recommended.