摘要1例68岁女性右侧桡骨远端多发骨折患者于石膏外固定手术后给予洛芬待因缓释片（每片含布洛芬0.2 g，磷酸可待因13 mg）3片口服，2次/ d。患者首次服药后约10 min，出现喘憋、心悸、大汗、面色苍白、咳嗽、咳痰、恶心、呕吐，听诊双肺可闻及哮鸣音。立即给予吸氧，多索茶碱和甲泼尼龙琥珀酸钠静脉滴注，并给予硫酸特布他林雾化液和布地奈德混悬液雾化吸入。2 h 后患者喘憋缓解，肺部哮鸣音消失。经追问病史，得知患者半年前在服用“去痛片”后出现喘息，1个月前在外院被诊断为支气管哮喘。

abstractsA 68-year-old female patient with multiple fractures of the right distal radius received oral compound codeine phosphate and ibuprofen sustained release tablets(containing ibuprofen 0. 2 g,codeine phosphate 13 mg per tablet)3 tablets twice daily after plaster external fixation. Ten minutes after the first administration,the patient developed wheezing,palpitation,pale,cough,expectoration,nausea,and vomiting. Oxygen inhalation,IV infusion of doxofylline and methylprednisolone sodium succinate for injection,and terbutaline sulphate solution for nebulization and budesonide suspension for inhalation were given immediately. Two hours after treatments,wheezing was relieved and wheezing rales in the lung disappeared. By asking the medical history,it was found that the patient had developed wheezing after taking somedon and was diagnosed as bronchial asthma 1 month ago in another hospital.