Pioglitazone:A review of analytical methods

二维码有效期 120s

摘要Pioglitazone is an oral anti-hyperglycemic agent. It is used for the treatment of diabetes mellitus type 2. It selectively stimulates nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-gamma). It was the tenth-best-selling drug in the U.S. in 2008. This article examines published analytical methods reported so far in the literature for the determination of pioglitazone in biological samples and pharmaceutical formulations. They include various techniques like electrochemical methods, spectrophotometry, capillary electrophoresis, high-performance liquid chromatography, liquid chromatography-electrospray ionization-tandem mass spectrometry and high-performance thin layer chromatography.

作者单位 Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research, Hyderabad NIPER-H, Balanagar, Hyderabad 500037, India ^[1] National Center for Mass Spectrometry, Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500607, India ^[2]

关键词 Pioglitazone Analytical methods Diabetes mellitus type 2

栏目名称 Original Articles

DOI 10.1016/j.jpha.2014.02.002

发布时间 2014-11-18

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交