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Greenness evaluation metric for analytical methods and software

摘要The focus of green analytical chemistry(GAC)is to minimize the negative impacts of analytical pro-cedures on human safety,human health,and the environment.Several factors,such as the reagents used,sample collection,sample processing,instruments,energy consumed,and the quantities of hazardous materials and waste generated during analytical procedures,need to be considered in the evaluation of the greenness of analytical assays.In this study,we propose a greenness evaluation metric for analytical methods(GEMAM).The new greenness metric is simple,flexible,and comprehensive.The evaluation criteria are based on both the 12 principles of GAC(SIGNIFICANCE)and the 10 factors of sample prep-aration,and the results are presented on a 0-10 scale.The GEMAM calculation process is easy to perform,and its results are easy to interpret.The output of GEMAM is a pictogram that can provide both qualitative and quantitative information based on color and number.

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作者 Tong Xin [1] Luyao Yu [1] Wenying Zhang [1] Yingxia Guo [1] Chuya Wang [1] Zhong Li [2] Jiansong You [3] Hongyu Xue [1] Meiyun Shi [4] Lei Yin [1] 学术成果认领
作者单位 School of Chemical Engineering,Ocean and Life Sciences,Dalian University of Technology,Panjin,Liaoning,124221,China [1] Pharmaceutical Department,Dalian Women & Children's Medical Group,Dalian,Liaoning,116012,China [2] Aim Honesty Biopharmaceutical Co.,Ltd.,Dalian,Liaoning,116600,China [3] School of Chemical Engineering,Ocean and Life Sciences,Dalian University of Technology,Panjin,Liaoning,124221,China;Aim Honesty Biopharmaceutical Co.,Ltd.,Dalian,Liaoning,116600,China [4]
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DOI 10.1016/j.jpha.2025.101202
发布时间 2025-11-24(万方平台首次上网日期,不代表论文的发表时间)
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药物分析学报(英文版)

药物分析学报(英文版)

2025年15卷7期

1667-1676页

SCIMEDLINEISTICCSCDCA

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