摘要目的 评估角膜塑形术(orthokeratology)联合单眼部分遮盖及精细训练法对屈光不正性弱视的效果.方法 前瞻性研究.分析2016年12月至2018年5月该院屈光不正性弱视患儿86例的临床资料,按随机数字表法分为两组,各43例.对照组,采取单眼部分遮盖及精细训练法;研究组,在对照组基础上增加角膜塑形术.两组均治疗6个月.结果 治疗6个月总有效率研究组(97.67％)高于对照组(81.40％)(x2=4.468,P=0.035);治疗6个月最佳矫正视力(logMAR)研究组(0.1±0.01)优于对照组(0.15±0.02) (t=14.663,P=0.000);视觉敏感度研究组高于对照组(t=4.428,P=0.000);研究组调节灵活度及调节幅度大于对照组、调节滞后量少于对照组(P=0.000).结论 采取角膜塑形术联合单眼部分遮盖及精细训练法治疗屈光不正性弱视患儿效果良好.

abstractsObjective To evaluate the efficacy of orthokeratology combined with monocular partial occlusion and fine training for the treatment of ametropic amblyopia.Methods A prospective study.The data of 86 children with ametropic amblyopia in this hospital from Dec.2016 to May 2018 were analyzed.All cases were randomly divided into two groups,with each group of 43 cases.All cases were partially coverd with a single eye.The control group adopted fine training.The research group underwent orthokeratology combined with fine training,and both groups were treated for 6 months.Results The total effective rate of the research group(97.67％)was higher than that of the control group (81.40％) (x2 =4.468,P =0.035).The best corrected visual acuity (LogMAR) of the research group (0.1 ±0.01) was better than that of the control group (0.15±0.02) (t =14.663,P=0.000).Visual sensitivity of the research group was higher than that of the control group(t =4.428,P =0.000).The adjustment flexibility and adjustment range of the research group were greater than that of the control group,and the adjustment hysteresis of the research group was less than that of the control group (P =0.000).Conclusion The combination of orthokeratology,monocular partial occlusion and fine training is effective for the treatment of children with ametropic amblyopia.