摘要目的:探讨三位一体案例式立体教学（case three-dimensional teaching method，CTTM）融合多媒体在肝脏传染病实习带教中的效果。方法:将本院2019年5月至2020年1月接收的25名肝脏传染病实习生作为对照组，2020年2月至2020年10月接收的25名实习生作为试验组。对照组进行案例教学和多媒体教学，试验组进行CTTM融合多媒体教学，两组均带教4周。比较两组教学后肝脏传染病相关理论和实践出科考核成绩、教学前后核心能力改变、教学认可度。运用SPSS 25.0进行 t检验和卡方检验。 结果:试验组教学后肝脏传染病相关理论[（92.45±7.23） vs. （81.21±7.11）]和实践[（93.27±6.68） vs. （81.23±6.26）]出科考核成绩均高于对照组；教学前两组核心能力评分差异均无统计学意义，教学后两组自主学习、分析与解决问题、医患沟通、团队协作等能力评分均高于教学前，且试验组评分均高于对照组（ P<0.05）；试验组实习生对教学能提高学习主动性、能巩固理论知识、能增强实践能力、能提高学习效率的认可率均高于对照组（ P<0.05）。 结论:在肝脏传染病实习生带教中采用CTTM融合多媒体教学，不仅可提高出科考核成绩，增强核心能力，还可提高实习生对教学的认可度。

abstractsObjective:To explore the effect of case three-dimensional teaching method (CTTM) combined with multimedia teaching on the practice teaching of liver infectious diseases.Methods:Twenty-five interns of liver infectious diseases received by The Second Hospital of Nanjing from May 2019 to January 2020 were taken as the control group, and 25 interns of liver infectious diseases received from February 2020 to October 2020 were taken as the observation group. The control group was given the conventional teaching mode including the conventional case teaching and the conventional multimedia teaching, while the observation group was given CTTM integrated with multimedia teaching method, and both groups were taught for 4 weeks. After teaching, the examination results of liver infectious disease related theory and practice, the changes of core competence before and after teaching, and the recognition of teaching were compared between the two groups. SPSS 25.0 was used for t test and chi-square test. Results:After teaching, the examination results of liver infectious disease related theory [(92.45±7.23) vs. (81.21±7.11)] and practice [(93.27±6.68) vs. (81.23±6.26)] in the observation group were higher than those in the control group. There was no significant difference in the scores of core competence between the two groups before teaching; after teaching, the scores of autonomous learning, problem analysis and solving, doctor-patient communication and teamwork ability of the two groups were higher than those before teaching, and the scores of observation group were significantly higher than those of the control group ( P<0.05). The recognition rates of interns in the observation group were higher than those in the control group in the improvement of learning initiative, the consolidation of theoretical knowledge, the enhancement of practical ability and the improvement of learning efficiency ( P<0.05). Conclusion:In the teaching of liver infectious disease interns, CTTM integrated with multimedia teaching method can not only improve the examination results, and enhance the core competence, but also improve the recognition of interns on the teaching mode.