A novel function of CREG in metabolic disorders

二维码有效期 120s

摘要Metabolic disorders are public health prob-lems that require prevention and new efficient drugs for treatment.Cellular repressor of E1A-stimulated genes(CREG)is ubiquitously expressed in mature tissues and cells in mammals and plays a critical role in keeping cells or tissues in a mature,homeostatic state.Recently,CREG turns to be an important mediator in the development of metabolic disorders.Here in this review,we briefly discuss the structure and molecular regulation of CREG along with the therapeutic strategy to combat the meta-bolic disorders.

作者 Yang Li ^[1] Xiaoxiang Tian ^[1] Quanyu Zhang ^[1] Chenghui Yan ^[1] Yaling Han ^[2] 学术成果认领

作者单位 Cardiovascular Research Institute and Department of Cardiology,General Hospital of Northern Theater Command,Shenyang 110016,Liaoning,China 6991 ^[1] Cardiovascular Research Institute and Department of Cardiology,General Hospital of Northern Theater Command,Shenyang 110016,Liaoning,China ^[2]

关键词 CREG insulin resistance metabolic disorders NAFLD obesity skeletal muscle energy metabolism

栏目名称 Reviews

DOI 10.1515/mr-2021-0031

发布时间 2023-08-02