Discovery of a series of dimethoxybenzene FGFR inhibitors with 5H-pyrrolo[2,3-b]pyrazine scaffold: structure-activity relationship, crystal structural characterization and in vivo study

导出原文传递学术成果认领

作者单位 Key Laboratory of Structure-Based Drug Design and Discovery of Ministry of Education, Shenyang Pharmaceutical University,Shenyang 110016, China;Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China ^[1] Division of Anti-tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China ^[2] Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China ^[3] Key Laboratory of Structure-Based Drug Design and Discovery of Ministry of Education, Shenyang Pharmaceutical University,Shenyang 110016, China ^[4]

关键词 Fibroblast growth factor Tyrosine kinase receptor Structure-based Crystallography Selectivity Hybrid 5-Hydrosulfonyl-5H-pyrrolo[2,3-b]pyrazine Inhibitor

栏目名称 Original Articles

发布时间 2019-05-16

基金项目

We are grateful for financial support from the National Natural Science Foundation of China the "Personalized Medicines—Molecular Signature-based Drug Discovery and Development",Strategic Priority Research Program of the Chinese Academy of Sciences the program for Innovative Research Team of the Ministry of Education the program for Liaoning Innovative Research Team at Shenyang Pharmaceutical University

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交

浏览1
被引0
下载0

药学学报（英文版）

2019年9卷2期

351-368页

相似文献

中文期刊
外文期刊
学位论文
会议论文

检索历史清除

Discovery of a series of dimethoxybenzene FGFR inhibitors with 5H-pyrrolo[2,3-b]pyrazine scaffold: structure-activity relationship, crystal structural characterization and in vivo study

药学学报（英文版）

相似文献

药学学报（英文版）

相关期刊

参考文献：
指定格式：	NoteExpress EndNote RefWorks NoteFirst

检索历史 清除

Discovery of a series of dimethoxybenzene FGFR inhibitors with 5H-pyrrolo[2,3-b]pyrazine scaffold: structure-activity relationship, crystal structural characterization and in vivo study

药学学报（英文版）

相似文献

药学学报（英文版）

相关期刊

检索历史清除