Construction of acetyl-CoA and DBAT hybrid metabolic pathway for acetylation of 10-deacetylbaccatin Ⅲ to baccatin Ⅲ
关键词
Microbial cell factoryBiosynthetic pathway of acetyl-CoABioconversion of 10-deacetylbaccatin Ⅲ to baccatin Ⅲ10-Deacetylbaccatin Ⅲ-10-β-O-acetyltransferaseDeacetylation of baccatin ⅢHigh-cell-density fermentationTaxol semi-synthesis
栏目名称
Original articles
发布时间
2021-12-16
基金项目
We thank Yingjin Yuan's lab
This work was supported by the National Key Research and Devel-opment Program of China (grant Nos,2018YFA0901900 and 2020YFA0908003)
the Drug Innovation Major Project
the National Natural Science Foundation of China
the CAMS Innovation Fund for Medical Sciences (CIFMS,(grant No,2017-I2M-2-004,2019-I2M-1-005,China)
and PUMC Disciplinary Development of Synthetic Biology
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药学学报(英文版)
2021年11卷10期
3322-3334页
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